Harry Dean Stanton – Lucky
David Lynch – Howard
Ron Livingston – Bobby Lawrence
Ed Begley Jr. – Dr. Christian Kneedler
Tom Skerritt – Fred
Beth Grant – Elaine
James Darren – Paulie
Barry Shabaka Henley – Joe
Yvonne Huff – Loretta
Hugo Armstrong – Vincent
Bertila Damas – Bibi
Ana Mercedes – Victoria
Sarah Cook – Debbie
Amy Claire – Frances
Ulysses Olmedo – Juan Wayne
Mikey Kampmann – Hipster
Otti Feder – Otti
Mouse – Mouse
Pam Sparks – Pam
Dan Gruenberg – Laughing Barfly
Johnny Glasser – Patron
Daniel R. Lawson – Patron
Liberace – Himself (archive footage)
Wonderful Cinema 